A Meta-Analysis of <span style="font-variant:small-caps; ">d</span>-Cycloserine in Exposure-Based Treatment
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چکیده
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متن کاملA meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy.
BACKGROUND Translational research suggests that D-cycloserine (DCS), a partial N-methyl-D-aspartate (NMDA) receptor agonist, might facilitate fear extinction and exposure therapy by either enhancing NMDA receptor function during extinction or by reducing NMDA receptor function during fear memory consolidation. This article provides a quantitative review of DCS-augmented fear extinction and expo...
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The treatment of anxiety is on the edge of a new era of combinations of pharmacologic and psychosocial interventions. A new wave of translational research has focused on the use of pharmacological agents as psychotherapy adjuvants using neurobiological insights into the mechanism of the action of certain psychological treatments such as exposure therapy. Recently, d-cycloserine (DCS) an antibio...
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ژورنال
عنوان ژورنال: The Journal of Clinical Psychiatry
سال: 2016
ISSN: 0160-6689
DOI: 10.4088/jcp.15r10334